Tandem BMT meetings workshop descriptions
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Appendix 1 Descriptions of the Workshop Talks
Martha Gillette. Grand Challenges in Understanding the Brain: Integrating chemistry, models, technology, & scale. Gillette highlighted the tremendous challenges in understanding the brain—a highly complex organ capable of sensation, integration, and actuation as well as multi-modal and highly plastic changes in response to experience. The brain is dynamic at multiple scales in both structure an...
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Chimerism after BMT has been documented by various genetic markers, RBC antigens, and, less frequently, by immunoglobulin allotypes. These markers are less sensitive than short tandem repeats (STRs), which provides a powerful tool for analysis of human polymorphisms. Application of STR analysis in patients undergoing allogeneic BMT has been used to detect mixed or complete chimerism, recurrent ...
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Volume 40, September 2000 TRANSFUSION 1071 Sickle cell disease (SCD) may be associated with considerable morbidity and mortality, particularly as patients reach adulthood.1 Among the various therapeutic options, allogeneic HPC transplantation is the only treatment with proven curative potential.1,2 However, the underlying disease recurs in about 10 percent of patients.2 Donor lymphocyte infusio...
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integrin (see figure). The binding of Kindlin to the integrin induces a conformational change in the integrin tail that facilitates the integrin to bind to another protein called Talin. Together, the binding of Kindlin and Talin to an integrin induces changes that allow the integrin to bind to its ligand. Until now, it appeared that the Kindlin-associated diseases—Kindler syndrome and leukocyte...
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ژورنال
عنوان ژورنال: Biology of Blood and Marrow Transplantation
سال: 2004
ISSN: 1083-8791
DOI: 10.1016/j.bbmt.2003.12.301